Novel Chalcone-Based Fluorescent Human Histamine H3 Receptor Ligands as Pharmacological Tools
نویسندگان
چکیده
منابع مشابه
Novel Chalcone-Based Fluorescent Human Histamine H3 Receptor Ligands as Pharmacological Tools
Novel fluorescent chalcone-based ligands at human histamine H(3) receptors (hH(3)R) have been designed, synthesized, and characterized. Compounds described are non-imidazole analogs of ciproxifan with a tetralone motif. Tetralones as chemical precursors and related fluorescent chalcones exhibit affinities at hH(3)R in the same concentration range like the reference antagonist ciproxifan (hH(3)R...
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ژورنال
عنوان ژورنال: Frontiers in Systems Neuroscience
سال: 2012
ISSN: 1662-5137
DOI: 10.3389/fnsys.2012.00014